Application
Western blot of Chemokine Receptor with Antibody dilution (1:500 in DilObuffer). MWM on right.| Product Name | CXCR2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to CXCR2CXCR2 is a receptor for interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family (subfamily, chemokine). Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries. |
| Immunogen | a synthetic peptide from human CXCR2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-FIPWB |
| IHC: Use at an assay dependent dilution. IP: Use at a dilution of 1/250. WB: Use at a dilution of 1/500. Predicted molecular weight: 55 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | IL8RB P25025 3579 CMKAR2 IL8R2 IL8RA CXCR2 146928 CDw128b CD182 |
|---|---|
| Target | CXCR2 |
| Tissue Specificity | detects CXCR2 expressed on intestinal microvascular cells. |
| Cellular Localization | Integral membrane protein. |
Application
Western blot of Chemokine Receptor with Antibody dilution (1:500 in DilObuffer). MWM on right.| Application Notes | IHC: Use at an assay dependent dilution. IP: Use at a dilution of 1/250. WB: Use at a dilution of 1/500. Predicted molecular weight: 55 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.02% Sodium Azide |
