| Product Name | CXCR3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [7K22] to CXCR3This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011] |
| Immunogen | Human recombinant CXCR3 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 7K22 |
| Host Species | Mouse |
| Tested Applications | FACSIHCNeut |
| IHC (frozen)(1:20-100)|FC(1:50-200)|Neutralization of CXCR3 bioactivity: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CD182 IP10-R Mig-R CKR-L2 chemokine (C-X-C motif) receptor 3 CD183 CMKAR3 GPR9 MigR |
|---|---|
| Target | CXCR3 |
| Tissue Specificity | This antibody was selected for its ability to detect human CXCR3. |
| Application Notes | IHC (frozen)(1:20-100)|FC(1:50-200)|Neutralization of CXCR3 bioactivity: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
