| Product Name | CXCR4 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [7L25] to CXCR4This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| Immunogen | Human recombinant CXCR4 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 7L25 |
| Host Species | Mouse |
| Tested Applications | FACSIHCNeut |
| IHC (frozen)(1:20-100)|FC(1:50-200)|Neutralization of CXCR4 bioactivity: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | WHIM NPY3R NPYY3R FB22 LAP3 chemokine (C-X-C motif) receptor 4 LCR1 NPYR HM89 HSY3RR NPYRL D2S201E CD184 LESTR A |
|---|---|
| Target | CXCR4 |
| Tissue Specificity | This antibody was selected for its ability to detect human CXCR4. |
| Application Notes | IHC (frozen)(1:20-100)|FC(1:50-200)|Neutralization of CXCR4 bioactivity: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
