Application
WB analysis of Jurkat cells using Cyclin H antibody at 1μg/ml.Application
IHC-P analysis of human lung tissue using Cyclin H antibody at 4.0-8.0μg/ml.| Product Name | Cyclin H antibody, C-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Cyclin HThe protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Nov 2010] |
| Immunogen | A synthetic peptide corresponding to a C-terminal region of Human Cyclin H |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 83%; Rabbit: 83%; Rat: 83% |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Synonyms | P34 CCNH CAK P37 |
|---|---|
| Target | Cyclin H |
| Molecular Weight(MW) | 38 KDa (note) |
Application
WB analysis of Jurkat cells using Cyclin H antibody at 1μg/ml.
Application
IHC-P analysis of human lung tissue using Cyclin H antibody at 4.0-8.0μg/ml.| Positive Control | Jurkat |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
