Application
CYFIP1 antibody detects CYFIP1 protein at cytosol on mouse pancreas by immunohistochemical analysis. Sample: Paraffin-embedded mouse pancreas. CYFIP1 antibody dilution: 1:500.| Product Name | CYFIP1 antibody |
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| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to CYFIP1 (cytoplasmic FMR1 interacting protein 1)Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth. Binds to F-actin but not to RNA. Regulator of epithelial morphogenesis. May act as an invasion suppressor in cancers. |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human CYFIP1. The exact sequence is proprietary. |
| Clonality | Polyclonal |
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| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-P |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Mouse |
| Predicted Reactivity | Human, Rat, Zebrafish, BovineHuman (100%), Rat (99%), Zebrafish (91%), Bovine (97%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | SHYC cytoplasmic FMR1 interacting protein 1 SRA1 P140SRA-1 |
|---|---|
| Target | CYFIP1 |
| Molecular Weight(MW) | 145 kDa (note) |
| Cellular Localization | Cytoplasm , perinuclear region , Cell projection , lamellipodium , ruffle , Cell junction , synapse , synaptosome |
Application
CYFIP1 antibody detects CYFIP1 protein at cytosol on mouse pancreas by immunohistochemical analysis. Sample: Paraffin-embedded mouse pancreas. CYFIP1 antibody dilution: 1:500.| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
