Application
Western blot analysis of anti-CYP1A1 Antibody (C-term) in mouse lung tissue lysates (35ug/lane). CYP1A1(arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CYP1A1 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.Application
Western blot analysis of anti-CYP1A1 Antibody (C-term) in K562 cell line lysates (35ug/lane). CYP1A1(arrow) was detected using the purified Pab.| Product Name | CYP1A1 antibody, C-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to CYP1A1 (C-term)This gene, CYP1A1, encodes a member of the cytochrome P45 superfamily of enzymes. The cytochrome P45 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq] |
| Immunogen | KLH conjugated synthetic peptide between 384~414 amino acids from the C-terminal region of human CYP1A1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| ELISA: Use at 1:1,000: |
|
| Species Reactivity | HumanMouse |
| Concentration | 0.2mg/ml |
| Gene Synonyms | P450 form 6 Cytochrome P4501A1 P450C P450 form6 P450P1 P450-P1 CYP1A1 CYPIA1 P450-C Cytochrome P450 1A1 P450 C P450 P1 |
|---|---|
| Target | CYP1A1 |
| Molecular Weight(MW) | 58.165 kDa (note) |
Application
Western blot analysis of anti-CYP1A1 Antibody (C-term) in mouse lung tissue lysates (35ug/lane). CYP1A1(arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CYP1A1 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application
Western blot analysis of anti-CYP1A1 Antibody (C-term) in K562 cell line lysates (35ug/lane). CYP1A1(arrow) was detected using the purified Pab.| Application Notes | ELISA: Use at 1:1,000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at at 2-8°C for up to 6 months. For long term storage, aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.09% (W/V) sodium azide |
