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CYP1A2 antibody

Catalog Number:OM248897
OM248897
Discount Price
OM248897-100ul
1~2 Week
100ul
OM248897-50ul
50ul
1~2 Week
Product Profile
Product Name CYP1A2 antibody
Antibody Type Primary Antibodies
Product description Mouse monoclonal antibody [6E2] to CYP1A2Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.
Immunogen Full length human recombinant protein of human CYP1A2 (NP_000752) produced in HEK293T cell.
Key Feature
Clonality Monoclonal
Isotype IgG2a
Clone Number 6E2
Host Species Mouse
Tested Applications FACSICC/IFIHCIHC-PWB
IHC 1:50 :
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms CYP1A2
CP12
P450(PA)
P3450
P3-450
Target CYP1A2
Tissue Specificity is specific for human CYP1A2 (NP_000752).
Application

Application

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of colon tissue using anti-CYP1A2 mouse monoclonal antibody. ( Dilution 1:50)

Application

Immunohistochemical staining of paraffin-embedded lung tissue using anti-CYP1A2 mouse monoclonal antibody. ( Dilution 1:50)

Application

Anti-CYP1A2 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected with CYP1A2

Application

Immunohistochemical staining of paraffin-embedded liver tissue using anti-CYP1A2 mouse monoclonal antibody. ( Dilution 1:50)

Application

Immunohistochemical staining of paraffin-embedded Kidney tissue using anti-CYP1A2 mouse monoclonal antibody. ( Dilution 1:50)

Application

Immunohistochemical staining of paraffin-embedded colon tissue using anti-CYP1A2 mouse monoclonal antibody. ( Dilution 1:50)

Application

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP1A2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP1A2.

Application

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of ovary tissue N93ing anti-CYP1A2 mouse monoclonal antibody. ( Dilution 1:50)

Application

Immunohistochemical staining of paraffin-embedded prostate tissue using anti-CYP1A2 mouse monoclonal antibody. ( Dilution 1:50)

Application

Immunohistochemical staining of paraffin-embedded pancreas tissue using anti-CYP1A2 mouse monoclonal antibody. ( Dilution 1:50)

Application

Immunohistochemical staining of paraffin-embedded Carcinoma of thyroid tissue using anti-CYP1A2 mouse monoclonal antibody. ( Dilution 1:50)

Application

Immunohistochemical staining of paraffin-embedded Carcinoma of prostate tissue using anti-CYP1A2 mouse monoclonal antibody. ( Dilution 1:50)

Application

Immunohistochemical staining of paraffin-embedded bladder tissue using anti-CYP1A2 mouse monoclonal antibody. ( Dilution 1:50)
Application Notes IHC 1:50 :
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4°C or aliquot into working amounts and store at -20°C. For long-term storage, store at -70°C (aliquotted). Avoid repeated freeze-thaw cycles.
Storage Buffer PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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