Application
WB analysis of human fetal muscle tissue using CYP2C19 antibody at 1.0μg/ml.Application
WB analysis of human B lymphoblast cells using CYP2C19 antibody at 1.0μg/ml.Application
WB analysis of human placenta tissue using CYP2C19 antibody at 0.2-1μg/ml.| Product Name | CYP2C19 antibody, Internal |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to CYP2C19This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008] |
| Immunogen | A synthetic peptide corresponding to an Internal region of Human CYP2C19 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Cow: 86%; Dog: 86%; Goat: 75%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 92%; Rabbit: 93%; Rat: 92%; Sheep: 86% |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CPCJ P450C2C P450IIC19 CYP2C CYP2C19 |
|---|---|
| Target | CYP2C19 |
| Molecular Weight(MW) | 56 KDa (note) |
Application
WB analysis of human fetal muscle tissue using CYP2C19 antibody at 1.0μg/ml.
Application
WB analysis of human B lymphoblast cells using CYP2C19 antibody at 1.0μg/ml.
Application
WB analysis of human placenta tissue using CYP2C19 antibody at 0.2-1μg/ml.| Positive Control | human B lymphoblast , human fetal muscle , human placenta |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
