Rabbit polyclonal to Human Cysteinyl Leukotriene Receptor 2 (CysLT2)Cysteinyl leukotriene receptor 2 (CysLT2) is a Chemoattractant Receptor that binds neutrophil chemoattractants such as cysteinyl leukotrienes. These ligands have potent proinflammatory activity and are implicated in many features of asthma including edema, bronchial constriction, and hyperreactivity (Bisgaard et al., 2000). Activation of cysteinyl leukotriene receptor 2 induces cell contraction and/or relaxation. CysLT2 expression has been reported in adrenal medulla, blood, brain, heart, kidney, lung, lymph node, ovary, placenta, prostate, pulmonary artery and vein, small intestine, and spleen. ESTs have been isolated from human kidney and liver/spleen libraries.
Immunogen
Synthetic peptide - KLH conjugated
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-P
Immunohistochemistry with formalin fixed paraffin embedded tissues. Not tested for other uses. IHC-P: Use at a dilution of 1/100 - 1/200.:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
CYSLT2 CYSLT2R HG57 HPN321 KPG_011 hGPCR21
Target
Cysteinyl Leukotriene Receptor 2 (CysLT2)
Application
Application
Immunohistochemical staining of human Spleen tissue sections using CysLT2 antibody
Application
Immunohistochemical staining of human Heart tissue sections using CysLT2 antibody
Positive Control
Heart tissue sections
Application Notes
Immunohistochemistry with formalin fixed paraffin embedded tissues. Not tested for other uses. IHC-P: Use at a dilution of 1/100 - 1/200.:
Additional Information
Form
Liquid
Storage Instructions
Store at 4 °C short term; For long term storage aliquot and store at -20 °C or below.