Mouse Monoclonal antibody [6F12-C7-D8] to Cystatin CThe cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth mu
Immunogen
Recombinant human cystatin c protein.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
6F12-C7-D8
Host Species
Mouse
Tested Applications
ELISA
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
cystatin C ARMD11 CST3
Target
Cystatin C
Application
Application
ELISA analysis of human Cystatin C (4μg/ml) using Cystatin C antibody [6F12-C7-D8] for capture and Cystatin C antibody [7F6-A5-F3] for detection.
Application Notes
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.