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Cytochrome P450 2C9 antibody, Internal

Catalog Number:OM249077
OM249077
Discount Price
OM249077-100ul
1~2 Week
100ul
OM249077-50ul
50ul
OM249077-20ul
20ul
1~2 Week
Product Profile
Product Name Cytochrome P450 2C9 antibody, Internal
Antibody Type Primary Antibodies
Product description Rabbit polyclonal to Cytochrome P450 2C9 (Internal)This gene encodes a member of the cytochrome P45 superfamily of enzymes. The cytochrome P45 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P45 genes on chromosome 1q24. [provided by RefSeq]
Immunogen KLH conjugated synthetic peptide between 243~273 amino acids from the Center region of human Cytochrome P450 2C9.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHC-PWB
ELISA: Use at 1:1,000:
Species Reactivity Human
Concentration 0.2mg/ml
Target Information
Gene Synonyms Cytochrome P450 2C9
Cytochrome P4502C9
CYP2C10
CYP2C9
Target Cytochrome P450 2C9
Molecular Weight(MW) 55.628 kDa (note)
Application

Application

Western blot analysis of anti-CYP2C9 Antibody (Center) in CEM cell line lysates (35ug/lane).CYP2C9(arrow) was detected using the purified Pab.

Application

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CYP2C9 antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application Notes ELISA: Use at 1:1,000:
Additional Information
Form Liquid
Storage Instructions Store at at 2-8°C for up to 6 months. For long term storage, aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.09% (W/V) sodium azide
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