| Product Name | Cytohesin 3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [CYT3 - 10] to Cytohesin 3This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1. |
| Immunogen | Recombinant full length GRP1 protein (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | CYT3-10 |
| Host Species | Mouse |
| Tested Applications | DIDELISAICC/IFWB |
| DID: Use at an assay dependent dilution. ELISA: Use at an assay dependent dilution. ICC: Use at an assay dependent dilution. WB: Use at a concentration of 2 - 4 μg/ml (determines using whole cell extract of NRK). Predicted molecular weight: 45 kDa and additional bands at 40 and 35 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Synonyms | 9265 605081 Cytohesin3 PSCD3 GRP1 ARNO3 O43739 Cytohesin 3 |
|---|---|
| Target | Cytohesin 3 |
| Tissue Specificity | Monoclonal Anti-GRP1 (Cytohesin 3, ARNO3) reacts specifically with GRP1, and does not cross-react with other members of the cytohesin family. |
| Positive Control | whole extract of NRK (normal rat kidney) cells |
|---|---|
| Application Notes | DID: Use at an assay dependent dilution. ELISA: Use at an assay dependent dilution. ICC: Use at an assay dependent dilution. WB: Use at a concentration of 2 - 4 μg/ml (determines using whole cell extract of NRK). Predicted molecular weight: 45 kDa and additional bands at 40 and 35 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Upon Receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 15mM Sodium Azide; Constituents: 0.01M PBS. pH 7.4 |
