| Product Name | Cytokeratin 1/2/3/4/5/6/7/8 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [Ks1-8] to Cytokeratin 1/2/3/4/5/6/7/8This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012] |
| Immunogen | Cytoskeletal proteins from cultured human MCF-7 cells. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | Ks1-8 |
| Host Species | Mouse |
| Tested Applications | IHC-FWB |
| IHC-F:1:50~1:100 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CYK8 KRT8 CK-8 KO K8 K2C8 CK8 CARD2 keratin 8 |
|---|---|
| Target | Cytokeratin 1/2/3/4/5/6/7/8 |
| Tissue Specificity | This antibody recognizes human type II cytokeratins, also known as the neutral to basic cytokeratins and destinguished from the type I or acidic cytokeratins. |
| Application Notes | IHC-F:1:50~1:100 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Prior to reconstitution store at +4°C. After reconstitution store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Phosphate buffered saline containing 0.09% Sodium Azide (NaN3) |
