Mouse monoclonal antibody [BA17] to Cytokeratin 19The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
BA17
Host Species
Mouse
Tested Applications
IHC-FIHC-PWB
Immunohistology - Paraffin: 1/50 - 1/100 Optimal dilution / concentration should be determined by the end user.:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
KRT19 K19 CK19 K1CS keratin 19
Target
Cytokeratin 19
Tissue Specificity
This antibody recognizes mouse cytokeratin 19.
Application
Application
IHC-P analysis of human breast cancer tissue using Cytokeratin 19 antibody. Antigen retrieval using citrate buffer at pH6.2.
Application Notes
Immunohistology - Paraffin: 1/50 - 1/100 Optimal dilution / concentration should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.