Rabbit Polyclonal antibody to Cytokeratin 3The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
Immunogen
A synthetic peptide corresponding to a C-terminal region of Human Cytokeratin 3
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Human: 100%; Rabbit: 79%
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
KRT3 K3 CK3
Target
Cytokeratin 3
Molecular Weight(MW)
64 KDa (note)
Application
Application
WB analysis of human fetal brain tissue using Cytokeratin 3 antibody at 0.2-1μg/ml.
Positive Control
human fetal brain
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.