Keratin, type II cytoskeletal 3, 65 kDa cytokeratin, Cytokeratin-3, CK-3, Keratin-3, K3, Type-II keratin Kb3, KRT3
Product description
The protein encoded by this gene is a member of the
keratin gene family. The type II cytokeratins consist of basic or
neutral proteins which are arranged in pairs of heterotypic keratin
chains coexpressed during differentiation of simple and stratified
epithelial tissues. This type II cytokeratin is specifically
expressed in the corneal epithelium with family member KRT12 and
mutations in these genes have been associated with Meesmann's
Corneal Dystrophy. The type II cytokeratins are clustered in a
region of chromosome 12q12-q13.1) Szaflik, J.P., et al. Mol. Vis. 14, 1713-1718 (2008) :
Immunogen
This KRT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-441 amino acids from the Central region of human KRT3.
Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.