| Product Name | Cytokeratin 7 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [LP1K] to Cytokeratin 7Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratins 7 and 8 are two closely related type II keratins characteristic of simple epithelia. Keratin 7 is less widespread than keratin 8 and is expressed in sebaceous and sweat glands and some cells of the inner hair root sheath. Keratin 7 is often co-expressed with keratin 19. |
| Immunogen | Sonicated cytoskeleton fractions ( insoluble in 1% Nonidet-P40) from SV40 transformed neonatal keratinocytes |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | LP1K |
| Host Species | Mouse |
| Tested Applications | IHCWB |
| IHC: Use at an assay dependent dilution. Poor reactivity with fixed tissue 54kDa. Some weak reactivity with keratin 8 and other type II keratins. WB: Use at an assay dependent dilution. Predicted molecular weight: 56 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | AmphibiansMammalian species |
| Concentration | 1mg/ml |
| Gene Synonyms | 3855 148059 K7 Cytokeratin7 MGC3625 MGC129731 KRT7 SCL K2C7 Cytokeratin 7 P08729 CK7 |
|---|---|
| Target | Cytokeratin 7 |
| Cellular Localization | Cytoplasmic |
| Application Notes | IHC: Use at an assay dependent dilution. Poor reactivity with fixed tissue 54kDa. Some weak reactivity with keratin 8 and other type II keratins. WB: Use at an assay dependent dilution. Predicted molecular weight: 56 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Phosphate-buffered saline |
