| Product Name | Cytokeratin Type I antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [AE1] to Cytokeratin Type IThe protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008] |
| Immunogen | Human epidermal keratins |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | AE1 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIHC-FIHC-P |
| ICC/IF:1:200~1:500 IHC-F:1:50~1:100 IHC-P:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseChickenMonkeyPigRatRabbitBovine |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Protein G |
| Gene Synonyms | EPPK keratin 1 CK1 EHK1 KRT1A K1 KRT1 EHK NEPPK |
|---|---|
| Target | Cytokeratin Type I |
| Tissue Specificity | Recognizes low molecular weight cytokeratins CK 10, CK14, CK15, CK16 and CK19 of the acidic family. |
| Application Notes | ICC/IF:1:200~1:500 IHC-F:1:50~1:100 IHC-P:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified antibody containing PBS 0.1% sodium azide. |
