Application
at 3g (per mg of protein lysate)detecting DAP12 on MHC ClassI postive cells (Lane 1) and NKp44 postive cells (Lane 2) by immunoprecipitation.| Product Name | DAP12 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to DAP12DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells. DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction. Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice, as well as presenile dementia and bone cysts in humans. |
| Immunogen | Recombinant full length protein (Human). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IPWB |
| IP: Use at a concentration of 2-4 μg/mg of protein lysate. WB: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Gene Synonyms | DAP12 TYROBP O43914 KARAP 221770 7305 PLOSL |
|---|---|
| Target | DAP12 |
| Cellular Localization | Plasma membrane |
Application
at 3g (per mg of protein lysate)detecting DAP12 on MHC ClassI postive cells (Lane 1) and NKp44 postive cells (Lane 2) by immunoprecipitation.| Positive Control | NKp44 positive cells. |
|---|---|
| Application Notes | IP: Use at a concentration of 2-4 μg/mg of protein lysate. WB: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.08% Sodium Azide; Constituents: PBS |
