| Product Name | DBC2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to DBC2Representational difference analysis (RDA) was the technique used to map a region on human chromosome 8p21 that contained a homozygous deletion several of the breast cancer specimens studied. The mapping of this region led to the identification of a gene with somatic mutations in breast cancer cells. This expression of this gene DBC2 (deleted in breast cancer) was extinguished in about half of the breast and lung cancer specimens that were examined, making it a good tumor suppressor candidate. The functional analysis of DBC2 found that expression of DBC2 in breast cancer cells missing DBC2 transcripts resulted growth inhibition. |
| Immunogen | Peptide mapping to the amino terminal domain of human DBC2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: Use at a dilution of 1/200. Predicted molecular weight: 83 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | KIAA0717 RHOBTB2 DBC2 Q9BYZ6 23221 607352 |
|---|---|
| Target | DBC2 |
| Application Notes | WB: Use at a dilution of 1/200. Predicted molecular weight: 83 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.1% Sodium azide, 0.2% gelatin.Constituents: PBS |
