Application
Sample (30 ug of whole cell lysate) A: Molt-4 B: Raji 5% SDS PAGE diluted at 1:1000| Product Name | Dbs antibody , N-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to DBS (MCF.2 cell line derived transforming sequence-like)Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42. |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human Dbs. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Mouse, RatMouse (90%), Rat (89%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | ARHGEF14 antibody DBS antibody FLJ12122 antibody KIAA0362 antibody OST antibody MCF2L antibody DBL's big sister antibody guanine nucleotide exchange factor DBS antibody MCF2 transforming sequence-like protein antibody MCF.2 cell line derived trans |
|---|---|
| Target | DBS |
| Molecular Weight(MW) | 128 kDa (note) (5) |
| Cellular Localization | Cytoplasm (By similarity) , Cell membrane; Peripheral membrane protein; Cytoplasmic side |
Application
Sample (30 ug of whole cell lysate) A: Molt-4 B: Raji 5% SDS PAGE diluted at 1:1000| Positive Control | 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
