Rabbit polyclonal antibody to DCCReceptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.
Immunogen
Synthetic peptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Optimal working dilutions should be determined experimentally be the end user.:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
CRCR1 DCC CRC18
Target
DCC
Application Notes
Optimal working dilutions should be determined experimentally be the end user.:
Additional Information
Form
Liquid
Storage Instructions
Product should be aliquoted and stored at -20∞C. Avoid repeated freeze/thaw cycles.