Rabbit Polyclonal antibody to DCPS (decapping enzyme, scavenger)Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA fragments shorter than 10 nucleotides that are produced by 3'->5' exosome-mediated mRNA decay. Releases m7GMP. Can also degrade m7GDP to m7GMP. Has no activity towards mRNA molecules longer than 25 nucleotides.
Immunogen
Recombinant protein encompassing a sequence within the center region of human DCPS. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Pig, BovineMouse (87%), Rat (85%), Pig (87%), Bovine (87%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
HINT-5 antibody HSL1 antibody DCPS antibody DCS-1 antibody scavenger mRNA-decapping enzyme DcpS antibody hint-related 7meGMP-directed hydrolase antibody homolog of C. elegans 7meGMP-directed hydrolase dcs-1 antibody heat shock-like protein 1 antibod
Molecular Weight(MW)
39 kDa (note) (2)
Cellular Localization
Cytoplasm , Nucleus
Application
Application
Sample (30 ug of whole cell lysate) A: A549 10% SDS PAGE diluted at 1:3000
Application
Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using DCPS antibody at 1:250 dilution.
Positive Control
A549 , HeLa , HepG2
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.