Application
Immunocytochemical staining of HeLa cells with Rabbit anti Human DcR2Application
Western blot analysis of HeLa cell whole cell lysate probed with Rabbit anti Human DcR2| Product Name | DcR2 / CD264 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to DcR2Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines. DR4 and DR5 are the recently identified functional receptors for TRAIL, and DcR1/TRID is a decoy receptor (1-3). Another member of the TRAIL receptor family was more recently identified and designatedDcR2, TRAIL-R4, or TRUNDD (4-6). DcR2 has an extracellular TRAIL-binding domain but lacks intracellular death domain and does not induce apoptosis. Like DR4and DR5, DcR2 transcript is widely expressed in normal human tissues. Overexpression of DcR2 attenuated TRAIL-induced apoptosis. |
| Immunogen | Peptide corresponding to amino acids 249 to 263of human DcR2 precursor (4-6). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFWB |
| For WB: Use at dilution of 1:1,000 to 1:2,000. Optimal concentrations/dilutions should be determined by the researcher.: |
|
| Species Reactivity | Human |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | TNFRSF10D DcR2 603614 Q9UBN6 TRUNDD TRAILR4 8793 |
|---|---|
| Target | DcR2 |
| Tissue Specificity | Human CdR2 |
Application
Immunocytochemical staining of HeLa cells with Rabbit anti Human DcR2
Application
Western blot analysis of HeLa cell whole cell lysate probed with Rabbit anti Human DcR2| Positive Control | HeLa whole cell lysate |
|---|---|
| Application Notes | For WB: Use at dilution of 1:1,000 to 1:2,000. Optimal concentrations/dilutions should be determined by the researcher.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | PBS, pH 7.4 with 0.02% sodium azide as preservative |
