| Product Name | Dectin-1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Dectin-1 (C-type lectin domain family 7, member A)This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq] |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Dectin-1. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Predicted Reactivity | Human, Rhesus MonkeyHuman (100%), Rhesus Monkey (100%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | BGR antibody, CANDF4 antibody, CLECSF12 antibody, DECTIN1 antibody, CLEC7A antibody, dendritic cell-associated C-type lectin 1 antibody, C-type lectin superfamily member 12 antibody, dectin-1 antibody, C-type lectin domain family 7 member A antibody, beta- |
|---|---|
| Target | DECTIN-1 |
| Molecular Weight(MW) | 28 kDa (note) |
| Cellular Localization | Membrane , Isoform 5: Cytoplasm , Isoform 6: Cytoplasm , Isoform 7: Cytoplasm |
| Positive Control | Synthetic peptide: 1:8,000 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
