| Product Name | DEDD2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal to DEDD2A novel Death Effector Domain-containing protein, DEDD2, is closest in amino acid sequence homology to Death Effector Domain-containing DNA-binding protein, DEDD. DEDD2 is expressed widely in adult human tissues with highest levels in liver, kidney and peripheral blood leukocytes. DEDD2 interacts with FLIP, but not with FADD or Caspase 8. Over-expression of DEDD2 induces moderate apoptosis and results in substantial sensitization to apoptosis induced by Fas(CD95/APO-1), TRAIL(Apo2L), or FADD. These findings suggest that DEDD2 is involved in the regulation of nuclear events mediated by the extrinsic apoptosis pathway. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| Not tested. The investigator should determine the optimal dilution for a specific application such as immunohistochemistry. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Serum |
| Gene Synonyms | FLAME-3, FLAME3, DEDD2, 162989, Q8WXF8, FLAME 3 |
|---|---|
| Target | DEDD2 |
| Tissue Specificity | Reacts with residues 144-129 of the DEDD2 protein. |
| Application Notes | Not tested. The investigator should determine the optimal dilution for a specific application such as immunohistochemistry. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | 100 µl serum containing 0.02% sodium azide. |
