| Product Name | delta Opioid receptor antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to Delta Opioid ReceptorThis protein functions as an inhibitor for neurotransmittors release by reducing calcium ion currents and increasing potassium ion conductance. Jordan and Devi (1999) provided biochemical and pharmacologic evidence for the heterodimerization of 2 fully functional opioid receptors, kappa (OPRK1; 165196) and delta. This results in a new receptor that exhibits ligand binding and functional properties that are distinct from those of either receptor. Furthermore, the kappa-delta heterodimer synergistically binds highly selective agonists and potentiates signal transduction. Pharmacologic and electrophysiologic evidence indicates that opioid receptors are involved in the mechanism of heroin dependence. Thus, opioid receptors are appropriate candidate genes for case-control association studies of heroin dependence Xu et al. (2002). |
| Immunogen | Synthetic peptide: TACTPSDGPGGGAAA, corresponding to amino acids 358-372 of Rat Delta Opioid Receptor. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IF |
| ICC: Use at a dilution of 1/1000. Optimal dilutions/concentrations should be determined by the end user. NOT recommended for tissue section staining. For studies of neuronal tissue, use GTX10271. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | OPRD1, delta Opioid receptor, 24613, P41143, OPRD, 4985, 165195 |
|---|---|
| Target | delta Opioid receptor |
| Application Notes | ICC: Use at a dilution of 1/1000. Optimal dilutions/concentrations should be determined by the end user. NOT recommended for tissue section staining. For studies of neuronal tissue, use GTX10271. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.05% Sodium Azide; Constituents: Whole Serum |
