Application
Whole cell extract (30 μg) was separated by 5% SDS-PAGE, and the membrane was blotted with Desmoglein 1 antibody diluted at 1:500.| Product Name | Desmoglein 1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Desmoglein 1 (desmoglein 1)Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus. [provided by RefSeq] |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Desmoglein 1. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | SPPK1 , DG1 , desmoglein 1 , DSG , CDHF4 , DSG1 , PPKS1 |
|---|---|
| Target | Desmoglein 1 |
| Molecular Weight(MW) | 114 kDa (note) |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein , Cell junction , desmosome , Cell membrane , Cell junction , desmosome |
Application
Whole cell extract (30 μg) was separated by 5% SDS-PAGE, and the membrane was blotted with Desmoglein 1 antibody diluted at 1:500.| Positive Control | A375 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative. |
