Application
Western blot analysis of extracts of various cells, using DSP antibody.Application
Immunohistochemistry of paraffin-embedded human liver injury using DSP antibody at dilution of 1:100 (400x lens).Application
Immunohistochemistry of paraffin-embedded mouse heart using DSP antibody at dilution of 1:100 (40x lens).Application
Immunohistochemistry of paraffin-embedded human stomach cancer using DSP antibody at dilution of 1:100 (40x lens).| Product Name | Desmoplakin antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to DesmoplakinDesmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus. [provided by RefSeq, Jul 2008] |
| Immunogen | A synthetic peptide of human DSP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCIHC-PWB |
| WB 1:500 - 1:2000, IHC 1:50 - 1:200: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | DSP DPI DPII DCWHKTA desmoplakin DP |
|---|---|
| Target | Desmoplakin |
Application
Western blot analysis of extracts of various cells, using DSP antibody.
Application
Immunohistochemistry of paraffin-embedded human liver injury using DSP antibody at dilution of 1:100 (400x lens).
Application
Immunohistochemistry of paraffin-embedded mouse heart using DSP antibody at dilution of 1:100 (40x lens).
Application
Immunohistochemistry of paraffin-embedded human stomach cancer using DSP antibody at dilution of 1:100 (40x lens).| Application Notes | WB 1:500 - 1:2000, IHC 1:50 - 1:200: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
