| Product Name | DHX58 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to DHX58 (DEXH (Asp-Glu-X-His) box polypeptide 58)Participates in innate immune defense against viruses. Upon interaction with intracellular dsRNA produced during viral replication, triggers a transduction cascade which results in the induction and expression of antiviral cytokines such as IFN-beta and RANTES (CCL5). The RNA helicase domain may recognize and structurally modify viral RNA to facilitate detection by DDX58/RIG-I or by IFIH1/MDA5 whose affinity for dsRNA is lower. |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human DHX58. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Predicted Reactivity | Human, Mouse, RatHuman (100%), Mouse (81%), Rat (80%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | D11LGP2 antibody D11lgp2e antibody LGP2 antibody DHX58 antibody RLR antibody probable ATP-dependent helicase LGP2 antibody probable ATP-dependent RNA helicase DHX58 antibody protein D11Lgp2 homolog antibody RNA helicase LGP2 antibody RIG-I-like re |
|---|---|
| Molecular Weight(MW) | 77 kDa (note) |
| Cellular Localization | Cytoplasm |
| Positive Control | Target recombinant protein |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
