Mouse monoclonal antibody [4G7] to DKK3This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Immunogen
The immunogen corresponding to human DKK3 expressed in E. Coli.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4G7
Host Species
Mouse
Tested Applications
ELISAFACSWB
ELISA: 1/10000.:
Species Reactivity
HumanMonkey
Concentration
1mg/ml
Target Information
Gene Synonyms
REIC RIG
Target
DKK3
Molecular Weight(MW)
38 kDa (note)
Application
Application
Western blot analysis using DKK3 mAb against HEK293 (1), MCF-7 (2) and HL7702 (3) cell lysate.
Application
Flow cytometric analysis of MCF-7 cells using anti-DKK3 mAb (green) and negative control (purple).
Application Notes
ELISA: 1/10000.:
Additional Information
Form
Liquid
Storage Instructions
Store at 4℃, for long term storage, store at -20℃.