Rabbit Polyclonal antibody to DLC1 (deleted in liver cancer 1)This gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers. Alternative splicing at this locus results in several transcript variants encoding different isoforms. [provided by RefSeq]
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human DLC1. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, DogMouse (100%), Dog (100%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
ARHGAP7 antibody FLJ21120 antibody HP antibody STARD12 antibody p122-RhoGAP antibody DLC1 antibody StAR-related lipid transfer (START) domain containing 12 antibody rho-type GTPase-activating protein 7 antibody deleted in liver cancer 1 variant 2 a
Molecular Weight(MW)
171 kDa (note) (2)
Cellular Localization
Cytoplasm
Application
Application
Sample(30 μg of whole cell lysate) A:MOLT4 7.5% SDS PAGE diluted at 1:1500
Application
Immunohistochemical analysis of paraffin-embedded Pheochromocytoma xenograft, using DLC1 antibody at 1:100 dilution.
Positive Control
H1299 , HeLaS3 , HepG2 , Molt-4 , Raji
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.