| Product Name | DLK/MAP3K12 antibody , N-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to DLK/MAP3K12 (mitogen-activated protein kinase kinase kinase 12)The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human ZPK. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Predicted Reactivity | Human, Mouse, Rat, Zebrafish, Xenopus laevis, Rhesus Monkey, BovineHuman (100%), Mouse (100%), Rat (100%), Zebrafish (90%), Xenopus laevis (93%), Rhesus Monkey (100%), Bovine (100%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | DLK antibody MEKK12 antibody MUK antibody ZPK antibody ZPKP1 antibody MAP3K12 antibody protein kinase MUK antibody MAPK-upstream kinase antibody dual leucine zipper bearing kinase antibody leucine zipper protein kinase antibody mixed lineage kina |
|---|---|
| Target | ZPK |
| Molecular Weight(MW) | 93 kDa (note) |
| Cellular Localization | Cytoplasm (By similarity) , Membrane; Peripheral membrane protein |
| Positive Control | Target recombinant protein |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
