| Product Name | DLK1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [9D8] to DLK1This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010] |
| Immunogen | Human recombinant Pref-1 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2 |
| Clone Number | 9D8 |
| Host Species | Mouse |
| Tested Applications | FACSWB |
| WB(1:500-1000)|FC(1:20-200): |
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| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | delta-like 1 homolog (Drosophila) PREF1 DLK ZOG FA1 DLK1 Delta1 DLK-1 pG2 |
|---|---|
| Target | Pref-1 |
| Tissue Specificity | This antibody was selected for its ability to specifically detect human DLK1 / Pref-1. |
| Application Notes | WB(1:500-1000)|FC(1:20-200): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS |
