Rabbit Polyclonal antibody to DMRT1 (doublesex and mab-3 related transcription factor 1)This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human DMRT1. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
PigPig (84%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
DMT1 antibody DMRT1 antibody DM domain expressed in testis 1 antibody doublesex- and mab-3-related transcription factor 1 antibody DM domain expressed in testis protein 1 antibody doublesex and mab-3 related transcription factor 1 antibody
Molecular Weight(MW)
39 kDa (note)
Cellular Localization
Nucleus
Application
Application
Sample (30 ug of whole cell lysate) A: K562 10% SDS PAGE diluted at 1:3000
Positive Control
K562
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.