Rabbit Polyclonal antibody to DNAJC2This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq, Jul 2008]
Immunogen
Recombinant protein of human DNAJC2
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ICC/IFWB
WB 1:500 - 1:2000, IF 1:50 - 1:100:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
MPHOSPH11 MPP11 ZRF1 DnaJ (Hsp40) homolog subfamily C member 2 ZUO1
Target
DNAJC2
Molecular Weight(MW)
72 kDa (note)
Application
Application
Western blot analysis of extract of various cells, using DNAJC2 antibody.