Rabbit Polyclonal antibody to DOCK8This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Jun 2010]
Immunogen
DOCK8 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human DOCK8.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAIHC-PWB
IHC-P: 5 ug/mL:
Species Reactivity
HumanMouse
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
dedicator of cytokinesis 8 ZIR8 MRD2
Application
Application
Immunohistochemistry of DOCK8 in human spleen tissue with DOCK8 antibody at 5 ug/mL.
Application
Western blot analysis of DOCK8 in EL4 cell lysate with DOCK8 antibody at (A) 1 and (B) 2 ug/ml.
Application Notes
IHC-P: 5 ug/mL:
Additional Information
Form
Liquid
Storage Instructions
Be stored at 4oC for three months and -20oC, stable for up to one year.