Application
Sample (30 ug of whole cell lysate) A: Raji B: K562 C: NCI-H929 7.5% SDS PAGE diluted at 1:1000Application
DPYD antibody [N1N2], N-term detects DPYD protein at cytoplasm on H358 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded H358 xenograft. DPYD antibody [N1N2], N-term dilution: 1:500.| Product Name | DPYD antibody , N-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to DPYD (dihydropyrimidine dehydrogenase)The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human DPYD. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | DHP antibody DHPDHASE antibody DPD antibody MGC132008 antibody MGC70799 antibody DPYD antibody dihydrouracil dehydrogenase antibody dihydropyrimidine dehydrogenase [NADP+] antibody dihydrothymine dehydrogenase antibody dihydropyrimidine dehydrogen |
|---|---|
| Molecular Weight(MW) | 111 kDa (note) (3) |
Application
Sample (30 ug of whole cell lysate) A: Raji B: K562 C: NCI-H929 7.5% SDS PAGE diluted at 1:1000
Application
DPYD antibody [N1N2], N-term detects DPYD protein at cytoplasm on H358 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded H358 xenograft. DPYD antibody [N1N2], N-term dilution: 1:500.| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
