Application
DR3 antibody detects TNFRSF25 protein at cytosol on AGS xenograft by immunohistochemical analysis. Sample: Paraffin-embedded AGS xenograft. DR3 antibody dilution: 1:500.Application
DR3 antibody detects TNFRSF25 protein by Western blot analysis. A. 30 µg Raji whole cell lysate/extract B. 30 µg K562 whole cell lysate/extract 10 % SDS-PAGE DR3 antibody dilution: 1:1000| Product Name | DR3 antibody |
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| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to DR3 (tumor necrosis factor receptor superfamily, member 25)The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human DR3. The exact sequence is proprietary. |
| Clonality | Polyclonal |
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| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | APO-3 antibody DDR3 antibody DR3 antibody LARD antibody TNFRSF12 antibody TR3 antibody TRAMP antibody WSL-1 antibody WSL-LR antibody TNFRSF25 antibody apoptosis-mediating receptor TRAMP antibody tumor necrosis factor receptor superfamily member |
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| Molecular Weight(MW) | 45 kDa (note) |
Application
DR3 antibody detects TNFRSF25 protein at cytosol on AGS xenograft by immunohistochemical analysis. Sample: Paraffin-embedded AGS xenograft. DR3 antibody dilution: 1:500.
Application
DR3 antibody detects TNFRSF25 protein by Western blot analysis. A. 30 µg Raji whole cell lysate/extract B. 30 µg K562 whole cell lysate/extract 10 % SDS-PAGE DR3 antibody dilution: 1:1000| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
