Application
WB ImageSample (30 ug of whole cell lysate) A: HeLa B: HCT116 10% SDS PAGE diluted at 1:1000| Product Name | DR5 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to DR5 (tumor necrosis factor receptor superfamily, member 10b)The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human DR5. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | CD262 antibody DR5 antibody KILLER antibody KILLER/DR5 antibody TRAIL-R2 antibody TRAILR2 antibody TRICK2 antibody TRICK2A antibody TRICK2B antibody TRICKB antibody ZTNFR9 antibody TNFRSF10B antibody Fas-like protein antibody tumor necrosis fa |
|---|---|
| Molecular Weight(MW) | 48 kDa (note) |
Application
WB ImageSample (30 ug of whole cell lysate) A: HeLa B: HCT116 10% SDS PAGE diluted at 1:1000| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
