Application
WB analysis of mouse kindey, mouse brain, HCT116 and HeLa lysates using DR5 antibody.Application
ICC/IF analysis of HeLa cells using DR5 antibody at a dilution of 1:100.| Product Name | DR5 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [7F4-F8-G11] to DR5The protein encoded by this gene is a member of the TNF-receptor superfamily,and contains an intracellular death domain.This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand(TNFSF10/TRAIL/APO-2L),and transduces an apoptosis signal.Studies with FADD-deficient mice suggested that FADD,a death domain containing adaptor protein,is required for the apoptosis mediated by this protein.Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.[provided by RefSeq,Mar 2009] |
| Immunogen | Purified recombinant human TNFRSF10B protein fragments expressed in E.coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | ICC/IFWB |
| ICC/IF:1:200~1:500 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | TNFRSF10B KILLER/DR5 TRICKB TRICK2 TRAIL-R2 ZTNFR9 tumor necrosis factor receptor superfamily member 10b TRICK2B CD262 TRAILR2 TRICK2A |
|---|---|
| Molecular Weight(MW) | 48kDa (note) |
Application
WB analysis of mouse kindey, mouse brain, HCT116 and HeLa lysates using DR5 antibody.
Application
ICC/IF analysis of HeLa cells using DR5 antibody at a dilution of 1:100.| Application Notes | ICC/IF:1:200~1:500 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide,0.1mg/mlBSA and 50% glycerol. |
