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DR5 antibody

Catalog Number:OM250512
OM250512
Discount Price
OM250512-100ul
1~2 Week
100ul
OM250512-50ul
50ul
1~2 Week
Product Profile
Product Name DR5 antibody
Antibody Type Primary Antibodies
Product description Mouse monoclonal antibody [DJR2-4] to DR5The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
Immunogen Extracellular domain of DR5-human IgG1 Fc fusion protein
Key Feature
Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications FACSICC/IF
Flow Cytometry: 1/10 - 1/20 Optimal dilution / concentration should be determined by the end user.:
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms TNFRSF10B
KILLER/DR5
TRICK2
TRAILR2
TRICK2A
KILLER
TRICKB
TRAIL-R2
ZTNFR9
tumor necrosis factor receptor superfamily
member 10b
TRICK2B
CD262
Application

Application

FACS analysis of BJAB cells using DR5 antibody [DJR2-4].
Application Notes Flow Cytometry: 1/10 - 1/20 Optimal dilution / concentration should be determined by the end user.:
Additional Information
Form Liquid
Storage Instructions Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage Buffer Phosphate buffered saline containing 0.09% Sodium Azide (NaN3)
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