| Product Name | DR5 antibody (Azide free) |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse Monoclonal antibody [HS201] to DR5The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009] |
| Immunogen | Recombinant human TRAIL-R2 (DR5). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | FACSICC/IFIPFunctional Assay |
| Functional Assay: Inhibition (blocks TRAIL-R2 mediated killing if applied in solution).: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | TRICKB tumor necrosis factor receptor superfamily member 10b TRICK2A TRICK2 KILLER/DR5 TRAILR2 CD262 TRICK2B TRAIL R2 TNFRSF10B KILLER ZTNFR9 |
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| Application Notes | Functional Assay: Inhibition (blocks TRAIL-R2 mediated killing if applied in solution).: |
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| Form | Liquid |
|---|---|
| Storage Instructions | Stable for at least 1 year after receipt when stored at -20°C. |
| Storage Buffer | PBS containing 10% glycerol. |
