Application
Western blot analysis of DYRK1A Antibody (N-term) in 293 cell line lysates (35ug/lane). DYRK1A (arrow) was detected using the purified Pab.Application
DYRK1A Antiboty (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DYRK1A Antiboty (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | DYRK1A antibody, N-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to DYRK1A (N-term)This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. [provided by RefSeq] |
| Immunogen | KLH conjugated synthetic peptide between 114~144 amino acids from the N-terminal region of human DYRK1A. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| ELISA: Use at 1:1,000: |
|
| Species Reactivity | Human |
| Concentration | 0.2mg/ml |
| Purification | Protein A |
| Gene Synonyms | HP86 Protein kinase minibrain homolog Dual specificity YAK1related kinase DYRK1A Dual specificity YAK1-related kinase MNBH hMNB |
|---|---|
| Molecular Weight(MW) | 85.453 kDa (note) |
Application
Western blot analysis of DYRK1A Antibody (N-term) in 293 cell line lysates (35ug/lane). DYRK1A (arrow) was detected using the purified Pab.
Application
DYRK1A Antiboty (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DYRK1A Antiboty (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | ELISA: Use at 1:1,000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at at 2-8°C for up to 6 months. For long term storage, aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.09% (W/V) sodium azide |
