Rabbit Polyclonal antibody to EAAT3This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect. [provided by RefSeq, Mar 2010]
Immunogen
A synthetic peptide corresponding to a N-terminal region of Human EAAT3.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Dog: 77%; Human: 100%; Mouse: 85%; Rat: 92%
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
EAAC1 SLC1A1 EAAT3
Target
EAAT3
Molecular Weight(MW)
57 KDa (note)
Application
Application
WB analysis of PANC1 cells using SLC1A1 antibody at 0.2-1μg/ml.
Positive Control
PANC1
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.