Rabbit polyclonal antibody to ECMStearoyl-CoA desaturase (SCD) is a regulatory enzyme involved in the synthesis of oleate and palmitoleate. Oleate and palmitoleate are the main components of membrane phospholipid, triglycerides and cholesterol esters. SCD plays an important role in cellular cholesterol homeostasis and also in the secretion processes of triacylglycerol and phospholipid. Inhibition of SCD could be a useful treatment for metabollic disorders such as obesity and hepatic steatosis.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~61 kDa ECM-1 of human, mouse, and rat origins. Reactivity to other species has not been tested.:
Species Reactivity
HumanMouseRat
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
extracellular matrix protein1 ECM1 extracellular matrix protein extracellular matrix protein 1
Target
ECM
Tissue Specificity
This antibody is specific for ECM.
Application
Application
Western blot analysis of ECM-1 in 3T3 cell lysate.
Application Notes
Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~61 kDa ECM-1 of human, mouse, and rat origins. Reactivity to other species has not been tested.:
Additional Information
Form
Liquid
Storage Instructions
The antibody solution should be gently mixed before use. Stored at -20 °C for future use.