| Product Name | EDG3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [AS61] to EDG3EDG3 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG3 is sphingosine-1-phosphate. There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG3 is expressed in heart, placenta, kidney, and liver tissue. |
| Immunogen | Synthetic peptide to C-terminal region of EDG3 (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Mouse |
| Tested Applications | WB |
| WB: Use at a dilution of 1/10,000. Detects a band of approximately 45 kDa (predicted molecular weight: 42.2 kDa). Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | 601965 FLJ37523 1903 EDG-3 S1PR3 Q99500 MGC71696 S1P3 LPB3 EDG3 EDG 3 |
|---|
| Application Notes | WB: Use at a dilution of 1/10,000. Detects a band of approximately 45 kDa (predicted molecular weight: 42.2 kDa). Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Preservative: 0.08% sodium azide; Constituents: PBS |
