Application
Immunohistochemistry of EFCAB4B in human kidney tissue with EFCAB4B antibody at 10 μg/mL.Application
Immunofluorescence of EFCAB4B in human kidney tissue with EFCAB4B antibody at 20 μg/mL.Application
Western blot analysis of EFCAB4B in mouse kidney tissue lysate with EFCAB4B antibody at 1 ug/ml.| Product Name | EFCAB4B antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to EFCAB4BEFCAB4B, also known as Calcium release-activated calcium channel regulator 2A, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation. EFCAB4B acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration. A closely related protein, EFCAB4A, is likely to play a similar role as EFCAB4B, but the detailed function of EFCAB4A is still under investigation. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHC-PWB |
| ICC/IF:1:200~1:500 IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CRACR2A Calcium release-activated calcium channel regulator 2 EFhand calcium binding domain4B Calcium releaseactivated calcium channel regulator2 EFhand calcium binding domain 4B EFCAB4B Calcium releaseactivated calcium channel regulator 2 EF-hand c |
|---|---|
| Target | EFCAB4B |
| Tissue Specificity | This antibody is specific for EFCAB4B |
Application
Immunohistochemistry of EFCAB4B in human kidney tissue with EFCAB4B antibody at 10 μg/mL.
Application
Immunofluorescence of EFCAB4B in human kidney tissue with EFCAB4B antibody at 20 μg/mL.
Application
Western blot analysis of EFCAB4B in mouse kidney tissue lysate with EFCAB4B antibody at 1 ug/ml.| Positive Control | Blocking Peptide: |
|---|---|
| Application Notes | ICC/IF:1:200~1:500 IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS containing 0.02% sodium azide |
