| Product description |
Mouse monoclonal [S-21] to EGFEGF exerts its actions by binding to the EGFR, a 170 kDa protein. Activation of EGFR initiates diverse cellular pathways in response to toxic environmental stimuli, or to EGF binding to the receptor, the EGFR forms homo- or heterodimers with other family members. Each dimeric receptor complex initiates a distinct signaling pathway by recruiting different Src homology 2 (SH2) containing effector proteins. |