Rabbit Polyclonal antibody to EI24This gene has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The protein encoded by this gene contains six putative transmembrane domains and may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Immunogen
EI24 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human EI24.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAIHC-PWB
WB: 1 - 2 ug/ml. IHC-P: 5 ug/ml:
Species Reactivity
Rat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
PIG8 TP53I8 etoposide induced 2.4 EPG4
Target
EI24
Tissue Specificity
At least two isoforms of EI24 are known to exist; this antibody will only detect the larger isoform.
Application
Application
Immunohistochemistry of EI24 in rat liver tissue with EI24 antibody at 5 ug/mL.
Application
Western blot analysis of EI24 in rat liver tissue lysate with EI24 antibody at (A) 1 and (B) 2 ug/mL.
Application Notes
WB: 1 - 2 ug/ml. IHC-P: 5 ug/ml:
Additional Information
Form
Liquid
Storage Instructions
Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.